Order NO. D190682
产品描述
概述
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
应用
免疫印迹(WB)
属性
保存缓冲液 |
-20°C, PBS(pH 7.4) containing 0.03% Proclin300 and 50% glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P62993
|
靶点基因 ID |
2885
|
靶点全称 |
growth factor receptor bound protein 2
|
靶点别名 |
ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2
|
靶点研究领域 |
Signal Transduction
|
亚型 |
IgG1
|