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Order NO. D190719
小鼠抗CYP17A1单克隆抗体
英文名 Anti-CYP17A1 mouse monoclonal antibody
别名 cytochrome P450 family 17 subfamily A member 1; CPT7; CYP17; S17AH; P450C17
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human
克隆类型 Mouse Monoclonal 抗原 CYP17A1
编 号 规格 库存 目录价(¥) 您的价格(¥) 数 量
D190719-0050 50 ul 预计5日内发货 1280 1280
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D190719-0100 100 ul 预计5日内发货 2000 2000
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产品描述

概述

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

应用

免疫印迹(WB)

属性

保存缓冲液 -20°C, ascites with 0.02% sodium azide and 50% glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P05093
靶点基因 ID 1586
靶点全称 cytochrome P450 family 17 subfamily A member 1
靶点别名 CPT7; CYP17; S17AH; P450C17
靶点研究领域 Metabolism, Signal Transduction, Cancer, Cardiovascular
亚型 IgG2b
Sample Application

  • Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane 1-3: A549, HepG2 and Hela cell lysates, Primary antibody: D190719(CYP17A1 Antibody) at dilution 1/1000, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 5 minutes