Order NO. D190746
产品描述
概述
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.
应用
免疫印迹(WB),免疫荧光(IF),免疫沉淀(IP)
属性
保存缓冲液 |
-20°C, PBS(pH 7.4) containing 0.03% Proclin300 and 50% glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q05397
|
靶点基因 ID |
5747
|
靶点全称 |
protein tyrosine kinase 2
|
靶点别名 |
FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
|
靶点研究领域 |
Signal Transduction, Cardiovascular
|
亚型 |
IgG1
|