Order NO. D190751
产品描述
概述
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
应用
免疫印迹(WB),免疫沉淀(IP),免疫荧光(IF),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, PBS(pH 7.4) containing 0.02% sodium azide and 50% glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P12004
|
靶点基因 ID |
5111
|
靶点全称 |
proliferating cell nuclear antigen
|
靶点别名 |
ATLD2
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Cancer
|
亚型 |
IgG2b
|