Order NO. D190762
小鼠抗ZAP70单克隆抗体
| 英文名 | Anti-ZAP70 mouse monoclonal antibody | ||
| 别名 | zeta chain of T-cell receptor associated protein kinase 70; SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Mouse | 反应种属 | Human |
| 克隆类型 | Mouse Monoclonal | 抗原 | ZAP70 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D190762-0050 | 50 ul | 预计5日内发货 |
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| D190762-0100 | 100 ul | 预计5日内发货 |
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产品描述
概述
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
应用
免疫印迹（WB），免疫沉淀（IP）
属性
| 保存缓冲液 | -20°C, PBS(pH 7.4) containing 0.02% sodium azide and 50% glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | P43403 |
| 靶点基因 ID | 7535 |
| 靶点全称 | zeta chain of T-cell receptor associated protein kinase 70 |
| 靶点别名 | SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70 |
| 靶点研究领域 | Signal Transduction, Immunology |
| 亚型 | IgG2b |
Sample Application
