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Order NO. D190771
小鼠抗XRCC6单克隆抗体
英文名 Anti-XRCC6 mouse monoclonal antibody
别名 X-ray repair cross complementing 6; ML8; KU70; TLAA; CTC75; CTCBF; G22P1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Monkey
克隆类型 Mouse Monoclonal 抗原 XRCC6
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D190771-0050 50 ul 预计5日内发货
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D190771-0100 100 ul 预计5日内发货
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产品描述

概述

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

应用

免疫印迹(WB),免疫荧光(IF),免疫沉淀(IP)

属性

亚型 IgG1
靶点研究领域 Epigenetics and Nuclear Signaling, Cancer
靶点别名 ML8; KU70; TLAA; CTC75; CTCBF; G22P1
靶点全称 X-ray repair cross complementing 6
靶点基因 ID 2547
靶点 Uniprot 登记号 P12956
运输条件 2-8°C
保存缓冲液 -20°C, PBS(pH 7.4) containing 0.02% sodium azide and 50% glycerol
Sample Application

  • Gel: 6%SDS-PAGE, Lysate: 30 μg, Lane 1-4: A549, Hela, COS7 and K562 cell lysates , Primary antibody: D190771(XRCC6 Antibody) at dilution 1/1000, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 5 minutes

  • Immunoprecipitation analysis of Hela cell lysates using D190771(XRCC6 Antibody).

  • The image is immunofluorescence of Hela cells fixed with -20°C Methanol using D190771(XRCC6 Antibody) at dilution 1/200.
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