Order NO. D190771
产品描述
概述
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
应用
免疫印迹(WB),免疫荧光(IF),免疫沉淀(IP)
属性
亚型 |
IgG1
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Cancer
|
靶点别名 |
ML8; KU70; TLAA; CTC75; CTCBF; G22P1
|
靶点全称 |
X-ray repair cross complementing 6
|
靶点基因 ID |
2547
|
靶点 Uniprot 登记号 |
P12956
|
运输条件 |
2-8°C
|
保存缓冲液 |
-20°C, PBS(pH 7.4) containing 0.02% sodium azide and 50% glycerol
|