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Order NO. D190782
小鼠抗SIRT1单克隆抗体
英文名 Anti-SIRT1 mouse monoclonal antibody
别名 sirtuin 1; SIR2; SIR2L1; SIR2alpha
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human
克隆类型 Mouse Monoclonal 抗原 SIRT1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D190782-0050 50 ul 预计5日内发货
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D190782-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

应用

免疫印迹(WB),免疫沉淀(IP)

属性

保存缓冲液 -20°C, PBS(pH 7.4) containing 0.02% sodium azide and 50% glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q96EB6
靶点基因 ID 23411
靶点全称 sirtuin 1
靶点别名 SIR2; SIR2L1; SIR2alpha
靶点研究领域 Epigenetics and Nuclear Signaling, Metabolism, Cancer
亚型 IgG2b
Sample Application

  • Immunoprecipitation analysis of Hela cell lysates using D190782(SIRT1 Antibody).

  • Gel: 6%SDS-PAGE, Lysate: 30 μg, Lane 1-5: CEM, A549, Ramos, Jurkat and Hela cell lysates, Primary antibody: D190782(SIRT1 Antibody) at dilution 1/1000, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 5 minutes
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