Order NO. D190794
产品描述
概述
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
应用
免疫印迹(WB)
属性
保存缓冲液 |
-20°C, PBS(pH 7.4) containing 0.03% Proclin300 and 50% glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P06730
|
靶点基因 ID |
1977
|
靶点全称 |
eukaryotic translation initiation factor 4E
|
靶点别名 |
CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1
|
靶点研究领域 |
Epigenetics and Nuclear Signaling
|
亚型 |
lgG1
|