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Order NO. D190794
小鼠抗EIF4E单克隆抗体
英文名 Anti-EIF4E mouse monoclonal antibody
别名 eukaryotic translation initiation factor 4E; CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Mouse, Rat
克隆类型 Mouse Monoclonal 抗原 EIF4E
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D190794-0050 50 ul 预计5日内发货
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D190794-0100 100 ul 预计5日内发货
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产品描述

概述

The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.

应用

免疫印迹(WB)

属性

保存缓冲液 -20°C, PBS(pH 7.4) containing 0.03% Proclin300 and 50% glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P06730
靶点基因 ID 1977
靶点全称 eukaryotic translation initiation factor 4E
靶点别名 CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1
靶点研究领域 Epigenetics and Nuclear Signaling
亚型 lgG1
Sample Application

  • Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane 1-12: Jurkat, Hela, MCF7, K562, C6, 3T3, PC12, HepG2, CHO-K1, Raji, Raw264.7 and Ramos cell lysates, Primary antibody: D190794(EIF4E Antibody) at dilution 1/2000, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 5 minutes
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