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Order NO. D190803
小鼠抗PTPN6单克隆抗体
英文名 Anti-PTPN6 mouse monoclonal antibody
别名 protein tyrosine phosphatase, non-receptor type 6; HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human
克隆类型 Mouse Monoclonal 抗原 PTPN6
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D190803-0050 50 ul 预计5日内发货
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D190803-0100 100 ul 预计5日内发货
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产品描述

概述

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.

应用

免疫印迹(WB),免疫沉淀(IP)

属性

保存缓冲液 -20°C, PBS(pH 7.4) containing 0.03% Proclin300 and 50% glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P29350
靶点基因 ID 5777
靶点全称 protein tyrosine phosphatase, non-receptor type 6
靶点别名 HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1
靶点研究领域 Signal Transduction, Cancer, Developmental Biology
亚型 IgG2a
Sample Application

  • Immunoprecipitation analysis of Raji cell lysates using D190803(PTPN6 Antibody).

  • Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane 1-4: Human tonsil, Daudi, Jurkat and Raji cell lysates , Primary antibody: D190803(PTPN6 Antibody) at dilution 1/1000, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 5 minutes
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