Order NO. D190811
产品描述
概述
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.
应用
免疫印迹(WB)
属性
保存缓冲液 |
-20°C, PBS(pH 7.4) containing 0.03% Proclin300 and 50% glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P06733
|
靶点基因 ID |
2023
|
靶点全称 |
enolase 1
|
靶点别名 |
NNE; PPH; MPB1; ENO1L1; HEL-S-17
|
靶点研究领域 |
Metabolism, Epigenetics and Nuclear Signaling, Cancer
|
亚型 |
IgG1
|