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Order NO. D190813
小鼠抗RPS6单克隆抗体
英文名 Anti-RPS6 mouse monoclonal antibody
别名 ribosomal protein S6; S6
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Mouse, Rat, Monkey
克隆类型 Mouse Monoclonal 抗原 RPS6
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D190813-0050 50 ul 预计5日内发货
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D190813-0100 100 ul 预计5日内发货
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产品描述

概述

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

应用

免疫印迹(WB),免疫荧光(IF),免疫沉淀(IP)

属性

保存缓冲液 -20°C, PBS(pH 7.4) containing 0.03% Proclin300 and 50% glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P62753
靶点基因 ID 6194
靶点全称 ribosomal protein S6
靶点别名 S6
靶点研究领域 Epigenetics and Nuclear Signaling
亚型 lgG1
Sample Application

  • The image is immunofluorescence of Hela cells fixed with 4% Paraformaldehyde using D190813(RPS6 Antibody) at dilution 1/200.

  • Immunoprecipitation analysis of Hela cell lysates using D190813(RPS6 Antibody).

  • Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane 1-5: Ramos, Jurkat, C6, 3T3 and Hela cell lysates, Primary antibody: D190813(RPS6 Antibody) at dilution 1/2000, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 5 minutes
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