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Order NO. D191051
小鼠抗PRKAA1单克隆抗体
英文名 Anti-PRKAA1 mouse monoclonal antibody
别名 Protein kinase, AMP-activated, alpha 1 catalytic subunit; AMPK; AMPKa1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Mouse
克隆类型 mouse monoclonal 抗原 PRKAA1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D191051-0050 50 ul 现货
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D191051-0100 100 ul 现货
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产品描述

概述

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

应用

免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 Ascitic fluid with 0.05% sodium azide and 40% glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q13131
靶点基因 ID 5562
靶点全称 Protein kinase, AMP-activated, alpha 1 catalytic subunit
靶点别名 AMPK; AMPKa1
靶点研究领域 Signal Transduction, Cancer, Metabolism, Cardiovascular, Neuroscience
亚型 IgG1
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human esophagus cancer and Human gastric cancer tissue using D191051(PRKAA1 Antibody) at dilution 1/150. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Jurkat, 231 and NIH/3T3 cell lysates, Primary antibody: D191051(PRKAA1 Antibody) at dilution 1/600, Secondary antibody: Goat anti mouse IgG at 1/5000 dilution, Exposure time: 3 minutes
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