Order NO. D191054
产品描述
概述
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
应用
免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
Ascitic fluid with 0.05% sodium azide and 40% glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P28482/P27361
|
靶点基因 ID |
5594/5595
|
靶点全称 |
mitogen-activated protein kinase 1/3
|
靶点别名 |
ERK1, ERK2, ERK1/2
|
靶点研究领域 |
Signal Transduction, Cancer, Neuroscience
|
亚型 |
IgG2b
|