概述

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.

应用

免疫检测

属性

保存缓冲液	-20°C, 0.01M PBS (pH7.4), 0.15M NaCl. Avoid repeated freeze-thaw cycles.
运输条件	2-8°C
靶点 Uniprot 登记号	P08727
靶点基因 ID	3880
靶点全称	keratin 19
靶点别名	keratin 19; Cyfra21-1; K19; CK19; K1CS
靶点研究领域	Signal Transduction
亚型	IgG