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Order NO. D194531
小鼠抗BMPR1A单克隆抗体
英文名 Anti-BMPR1A mouse monoclonal antibody
别名 bone morphogenetic protein receptor type 1A; ALK3; SKR5; ALK-3; CD292; ACVRLK3; BMPR-1A; 10q23del
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Mouse
克隆类型 mouse monoclonal 抗原 BMPR1A
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D194531-0050 50 ul 预计5日内发货
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D194531-0100 100 ul 现货
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产品描述

概述

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

应用

免疫印迹(WB),免疫组织化学(IHC),流式细胞术(FCM)

属性

保存缓冲液 -20°C, Ascitic fluid with 0.05% sodium azide
运输条件 2-8°C
靶点 Uniprot 登记号 P36894
靶点基因 ID 657
靶点全称 bone morphogenetic protein receptor type 1A
靶点别名 ALK3; SKR5; ALK-3; CD292; ACVRLK3; BMPR-1A; 10q23del
靶点研究领域 Signal Transduction, Stem Cells, Cardiovascular, Metabolism
亚型 IgG1
相关文档
Sample Application

  • The image is flow cytometry analysis of HeLa cells using D194531(BMPR1A antibody) at dilution 1/400 (green) and negative control (purple).

  • The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using D194531(BMPR1A Antibody) at dilution 1/800. (Original magnification: ×200)

  • The image is immunohistochemistry of paraffin-embedded Human kidney tissue tissue using D194531(BMPR1A Antibody) at dilution 1/800. (Original magnification: ×200)

  • Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane 1-3: PC-3, K562 cell lysate and Mouse liver tissue lysate, Primary antibody: D194531(BMPR1A Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes
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