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Order NO. D194532
小鼠抗BMPR2单克隆抗体
英文名 Anti-BMPR2 mouse monoclonal antibody
别名 bone morphogenetic protein receptor type 2; BMR2; PPH1; BMPR3; BRK-3; POVD1; T-ALK; BMPR-II
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Mouse, Rat, Monkey
克隆类型 mouse monoclonal 抗原 BMPR2
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D194532-0050 50 ul 预计5日内发货
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D194532-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

应用

免疫印迹(WB), 免疫组织化学(IHC), 免疫荧光(IF)

属性

保存缓冲液 -20°C, Ascitic fluid with 0.05% sodium azide
运输条件 2-8°C
靶点 Uniprot 登记号 Q13873
靶点基因 ID 659
靶点全称 bone morphogenetic protein receptor type 2
靶点别名 BMR2; PPH1; BMPR3; BRK-3; POVD1; T-ALK; BMPR-II
靶点研究领域 Signal Transduction, Cardiovascular, Stem Cells
亚型 IgG1
相关文档
Sample Application

  • The image is immunofluorescence of Eca-109 cells using D194532(BMPR2 Antibody) at dilution 1/200 (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

  • The image is immunohistochemistry of paraffin-embedded Human muscle tissue tissue using D194532(BMPR2 Antibody) at dilution 1/800. (Original magnification: ×200)

  • The image is immunohistochemistry of paraffin-embedded Human kidney cancer tissue using D194532(BMPR2 Antibody) at dilution 1/800. (Original magnification: ×200)

  • Gel: 6%SDS-PAGE, Lysate: 20 μg, Lane 1-5: Hela, A431, NIH/3T3, COS-7 and PC-12 cell lysates, Primary antibody: D194532(BMPR2 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes
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