Order NO. D194532
产品描述
概述
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.
应用
免疫印迹(WB), 免疫组织化学(IHC), 免疫荧光(IF)
属性
保存缓冲液 |
-20°C, Ascitic fluid with 0.05% sodium azide
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q13873
|
靶点基因 ID |
659
|
靶点全称 |
bone morphogenetic protein receptor type 2
|
靶点别名 |
BMR2; PPH1; BMPR3; BRK-3; POVD1; T-ALK; BMPR-II
|
靶点研究领域 |
Signal Transduction, Cardiovascular, Stem Cells
|
亚型 |
IgG1
|