Order NO. D194548
产品描述
概述
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
应用
免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q86VB7
|
靶点基因 ID |
9332
|
靶点全称 |
CD163 molecule
|
靶点别名 |
M130; MM130; SCARI1
|
靶点研究领域 |
Cardiovascular, Immunology
|
亚型 |
IgG1
|