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Order NO. D194549
小鼠抗CD177单克隆抗体
英文名 Anti-CD177 mouse monoclonal antibody
别名 CD177 molecule; NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human
克隆类型 mouse monoclonal 抗原 CD177
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D194549-0050 50 ul 预计5日内发货
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D194549-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

应用

免疫印迹(WB),流式细胞术(FCM)

属性

保存缓冲液 -20°C, PBS (PH 7.4) containing 0.05% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q8N6Q3
靶点基因 ID 57126
靶点全称 CD177 molecule
靶点别名 NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP
靶点研究领域 Immunology
亚型 IgG2b
相关文档
Sample Application

  • The image is flow cytometry analysis of HL-60 cells using D194549(CD177 antibody) at dilution 1/400 (green) and negative control (red).

  • Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane 1-3: SPC-A-1, SK-MES-1 and PC-3 cell lysates, Primary antibody: D194549(CD177 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes
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