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编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D194553-0050 | 50 ul | 预计5日内发货 |
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D194553-0100 | 100 ul | 预计5日内发货 |
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概述
The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.
应用
免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 | -20°C, PBS (PH 7.4) containing 0.05% sodium azide. |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | P28907 |
靶点基因 ID | 952 |
靶点全称 | CD38 molecule |
靶点别名 | ADPRC1; ADPRC 1 |
靶点研究领域 | Cancer, Cardiovascular, Metabolism, Immunology, Stem Cells |
亚型 | IgG1 |