Order NO. D194564
产品描述
概述
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
应用
免疫印迹(WB),流式细胞术(FCM)
属性
保存缓冲液 |
-20°C, Ascitic fluid with 0.05% sodium azide
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P33151
|
靶点基因 ID |
1003
|
靶点全称 |
cadherin 5
|
靶点别名 |
7B4; CD144
|
靶点研究领域 |
Signal Transduction, Cardiovascular
|
亚型 |
IgG1
|