Order NO. D194593
产品描述
概述
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses.
应用
免疫印迹(WB),免疫组织化学(IHC),流式细胞术(FCM)
属性
保存缓冲液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P19525
|
靶点基因 ID |
5610
|
靶点全称 |
eukaryotic translation initiation factor 2 alpha kinase 2
|
靶点别名 |
PKR; PRKR; DYT33; LEUDEN; EIF2AK1; PPP1R83
|
靶点研究领域 |
Signal Transduction
|
亚型 |
IgG1
|