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Order NO. D194593
小鼠抗EIF2AK2单克隆抗体
英文名 Anti-EIF2AK2 mouse monoclonal antibody
别名 eukaryotic translation initiation factor 2 alpha kinase 2; PKR; PRKR; DYT33; LEUDEN; EIF2AK1; PPP1R83
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human
克隆类型 mouse monoclonal 抗原 EIF2AK2
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D194593-0050 50 ul 预计5日内发货
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D194593-0100 100 ul 预计5日内发货
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产品描述

概述

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses.

应用

免疫印迹(WB),免疫组织化学(IHC),流式细胞术(FCM)

属性

保存缓冲液 -20°C, PBS (PH 7.4) containing 0.05% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 P19525
靶点基因 ID 5610
靶点全称 eukaryotic translation initiation factor 2 alpha kinase 2
靶点别名 PKR; PRKR; DYT33; LEUDEN; EIF2AK1; PPP1R83
靶点研究领域 Signal Transduction
亚型 IgG1
相关文档
Sample Application

  • The image is flow cytometry analysis of A431 cells using D194593(EIF2AK2 antibody) at dilution 1/400 (green) and negative control (red).

  • The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using D194593(EIF2AK2 Antibody) at dilution 1/800. (Original magnification: ×200)

  • The image is immunohistochemistry of paraffin-embedded Human rectum cancer tissue using D194593(EIF2AK2 Antibody) at dilution 1/800. (Original magnification: ×200)

  • Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane 1-3: A431, THP-1, PC-12 cell lysates, Primary antibody: D194593(EIF2AK2 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes
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