Order NO. D194632
产品描述
概述
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9.
应用
免疫印迹（WB）, 免疫组织化学（IHC）, 免疫荧光（IF）, 流式细胞术（FCM）
属性
| 保存缓冲液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|
| 运输条件 |
2-8°C
|
| 靶点 Uniprot 登记号 |
P08887
|
| 靶点基因 ID |
3570
|
| 靶点全称 |
interleukin 6 receptor
|
| 靶点别名 |
IL6Q; gp80; CD126; HIES5; IL-6R; IL6RA; IL6RQ; IL-1Ra; IL-6RA; IL6QTL; IL-6R-1
|
| 靶点研究领域 |
Immunology, Stem Cells
|
| 亚型 |
IgG1
|
