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Order NO. D194632
小鼠抗IL6R单克隆抗体
英文名 Anti-IL6R mouse monoclonal antibody
别名 interleukin 6 receptor; IL6Q; gp80; CD126; HIES5; IL-6R; IL6RA; IL6RQ; IL-1Ra; IL-6RA; IL6QTL; IL-6R-1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Rat
克隆类型 mouse monoclonal 抗原 IL6R
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D194632-0050 50 ul 预计5日内发货
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D194632-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9.

应用

免疫印迹(WB), 免疫组织化学(IHC), 免疫荧光(IF), 流式细胞术(FCM)

属性

保存缓冲液 -20°C, PBS (PH 7.4) containing 0.05% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 P08887
靶点基因 ID 3570
靶点全称 interleukin 6 receptor
靶点别名 IL6Q; gp80; CD126; HIES5; IL-6R; IL6RA; IL6RQ; IL-1Ra; IL-6RA; IL6QTL; IL-6R-1
靶点研究领域 Immunology, Stem Cells
亚型 IgG1
相关文档
Sample Application

  • The image is flow cytometry analysis of Jurkat cells using D194632(IL6R antibody) at dilution 1/400 (green) and negative control (red).

  • The image is immunofluorescence of Hela cells using D194632(IL6R Antibody) at dilution 1/200 (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

  • The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using D194632(IL6R Antibody) at dilution 1/800. (Original magnification: ×200)

  • The image is immunohistochemistry of paraffin-embedded Human rectal cancer tissue using D194632(IL6R Antibody) at dilution 1/800. (Original magnification: ×200)

  • Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane 1-3: Jurkat, MOLT-4, THP-1 cell lysates, Primary antibody: D194632(IL6R Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes
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