Order NO. D194653
产品描述
概述
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
应用
免疫印迹(WB)
属性
亚型 |
IgG1
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Cancer, Signal Transduction
|
靶点别名 |
LEF-1; TCF10; TCF7L3; TCF1ALPHA
|
靶点全称 |
lymphoid enhancer binding factor 1
|
靶点基因 ID |
51176
|
靶点 Uniprot 登记号 |
Q9UJU2
|
运输条件 |
2-8°C
|
保存缓冲液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|