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Order NO. D194653
小鼠抗LEF1单克隆抗体
英文名 Anti-LEF1 mouse monoclonal antibody
别名 lymphoid enhancer binding factor 1; LEF-1; TCF10; TCF7L3; TCF1ALPHA
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human
克隆类型 mouse monoclonal 抗原 LEF1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D194653-0050 50 ul 预计5日内发货
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D194653-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

应用

免疫印迹(WB)

属性

亚型 IgG1
靶点研究领域 Epigenetics and Nuclear Signaling, Cancer, Signal Transduction
靶点别名 LEF-1; TCF10; TCF7L3; TCF1ALPHA
靶点全称 lymphoid enhancer binding factor 1
靶点基因 ID 51176
靶点 Uniprot 登记号 Q9UJU2
运输条件 2-8°C
保存缓冲液 -20°C, PBS (PH 7.4) containing 0.05% sodium azide.
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Sample Application

  • Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane: HepG2 cell lysate, Primary antibody: D194653(LEF1 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes
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