小鼠抗RAD50单克隆抗体,Anti-RAD50 mouse monoclonal antibody 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. D194705

小鼠抗RAD50单克隆抗体

英文名	Anti-RAD50 mouse monoclonal antibody
别名	RAD50 double strand break repair protein; NBSLD; RAD502; hRad50
相关类别	一抗	储存	冷冻（-20℃）
宿主	Mouse	反应种属	Human, Rat
克隆类型	mouse monoclonal	抗原	RAD50
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编号	规格	库存	目录价（￥）	您的价格（￥）	数量
D194705-0050	50 ul	预计5日内发货	1280	1280	－ +
D194705-0100	100 ul	预计5日内发货	2000	2000	－ +

产品描述

概述

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.

应用

免疫印迹（WB），免疫组织化学（IHC），流式细胞术（FCM）

属性

保存缓冲液	-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
运输条件	2-8°C
靶点 Uniprot 登记号	Q92878
靶点基因 ID	10111
靶点全称	RAD50 double strand break repair protein
靶点别名	NBSLD; RAD502; hRad50
靶点研究领域	Epigenetics and Nuclear Signaling
亚型	IgG2a

相关文档

Sample Application

The image is flow cytometry analysis of Hela cells using D194705(RAD50 antibody) at dilution 1/400 (green) and negative control (red).
The image is immunohistochemistry of paraffin-embedded Human esophageal cancer tissue using D194705(RAD50 Antibody) at dilution 1/800. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human rectum cancer tissue using D194705(RAD50 Antibody) at dilution 1/800. (Original magnification: ×200)
Gel: 6%SDS-PAGE, Lysate: 20 μg, Lane 1-2: C6 and HepG2 cell lysates, Primary antibody: D194705(RAD50 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes