Order NO. D194741
产品描述
概述
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
应用
免疫印迹(WB),流式细胞术(FCM)
属性
保存缓冲液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q07011
|
靶点基因 ID |
3604
|
靶点全称 |
TNF receptor superfamily member 9
|
靶点别名 |
ILA; 4-1BB; CD137; CDw137
|
靶点研究领域 |
Cancer, Immunology, Stem Cells
|
亚型 |
IgG1
|