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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D194754-0050 | 50 ul | 预计5日内发货 |
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| D194754-0100 | 100 ul | 预计5日内发货 |
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概述
This gene encodes a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. The encoded protein forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. This protein may also regulate neural tube closure, limb development and brown fat metabolism. This gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis, as well as metastatic recurrence. Mutations in this gene cause Saethre-Chotzen syndrome in human patients, which is characterized by craniosynostosis, ptosis and hypertelorism.
应用
免疫印迹（WB）, 免疫组织化学（IHC）, 免疫荧光（IF）, 流式细胞术（FCM）
属性
| 保存缓冲液 | -20°C, PBS (PH 7.4) containing 0.05% sodium azide. |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q15672 |
| 靶点基因 ID | 7291 |
| 靶点全称 | twist family bHLH transcription factor 1 |
| 靶点别名 | CRS; CSO; SCS; ACS3; CRS1; BPES2; BPES3; SWCOS; TWIST; bHLHa38 |
| 靶点研究领域 | Epigenetics and Nuclear Signaling, Cancer, Neuroscience, Cardiovascular, Developmental Biology |
| 亚型 | IgG1 |
