Order NO. D194822
产品描述
概述
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
应用
免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q14956
|
靶点基因 ID |
10457
|
靶点全称 |
glycoprotein nmb
|
靶点别名 |
NMB; HGFIN; PLCA3
|
靶点研究领域 |
Immunology, Cancer
|
亚型 |
IgG1
|