Order NO. D194830
产品描述
概述
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
应用
免疫印迹(WB),免疫荧光(IF),流式细胞术(FCM)
属性
保存缓冲液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
O60216
|
靶点基因 ID |
5885
|
靶点全称 |
RAD21 cohesin complex component
|
靶点别名 |
MGS; HR21; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21
|
靶点研究领域 |
Cancer, Epigenetics and Nuclear Signaling
|
亚型 |
IgG1
|