Order NO. D194875
产品描述
概述
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.
应用
免疫印迹(WB),免疫荧光(IF),流式细胞术(FCM)
属性
保存缓冲液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
O60664
|
靶点基因 ID |
10226
|
靶点全称 |
perilipin 3
|
靶点别名 |
PP17; TIP47; M6PRBP1
|
靶点研究领域 |
Signal Transduction
|
亚型 |
IgG2a,k
|