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Order NO. D194890
小鼠抗CASP3单克隆抗体
英文名 Anti-CASP3 mouse monoclonal antibody
别名 caspase 3; CPP32; SCA-1; CPP32B
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Mouse, Rat
克隆类型 mouse monoclonal 抗原 CASP3
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D194890-0050 50 ul 预计5日内发货
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D194890-0100 100 ul 现货
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产品描述

概述

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.

应用

免疫印迹(WB)

属性

保存缓冲液 -20°C, PBS (PH 7.4) containing 0.05% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 P42574
靶点基因 ID 836
靶点全称 caspase 3
靶点别名 CPP32; SCA-1; CPP32B
靶点研究领域 Cancer,Cell Biology,Neuroscience
亚型 IgG1
相关文档
Sample Application

  • Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane 1-6: Hela, Jurkat, HepG2, BCL-1, SK-BR-3, NIH/3T3 cell lysates, Primary antibody: D194890(CASP3 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes
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