Order NO. D194890
产品描述
概述
The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
应用
免疫印迹(WB)
属性
保存缓冲液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P42574
|
靶点基因 ID |
836
|
靶点全称 |
caspase 3
|
靶点别名 |
CPP32; SCA-1; CPP32B
|
靶点研究领域 |
Cancer,Cell Biology,Neuroscience
|
亚型 |
IgG1
|