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Order NO. D194899
小鼠抗CDK1单克隆抗体
英文名 Anti-CDK1 mouse monoclonal antibody
别名 cyclin dependent kinase 1; CDC2; CDC28A; P34CDC2
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Mouse, Rat, Monkey
克隆类型 mouse monoclonal 抗原 CDK1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D194899-0050 50 ul 预计5日内发货
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D194899-0100 100 ul 预计5日内发货
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产品描述

概述

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

应用

免疫印迹(WB), 免疫组织化学(IHC), 免疫荧光(IF)

属性

保存缓冲液 -20°C, Ascitic fluid with 0.05% sodium azide
运输条件 2-8°C
靶点 Uniprot 登记号 P06493
靶点基因 ID 983
靶点全称 cyclin dependent kinase 1
靶点别名 CDC2; CDC28A; P34CDC2
靶点研究领域 Epigenetics and Nuclear Signaling, Cancer, Neuroscience
亚型 IgG1
相关文档
Sample Application

  • The image is immunofluorescence of Eca-109 cells using D194899(CDK1 Antibody) at dilution 1/200 (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

  • The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using D194899(CDK1 Antibody) at dilution 1/800. (Original magnification: ×200)

  • The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using D194899(CDK1 Antibody) at dilution 1/800. (Original magnification: ×200)

  • Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane 1-9: Hela, Jurkat, K562, A431, MCF-7, RAW264.7, NIH/3T3, PC-12 and COS-7 cell lysates, Primary antibody: D194899(CDK1 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes
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