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Order NO. D194908
小鼠抗HDAC1单克隆抗体
英文名 Anti-HDAC1 mouse monoclonal antibody
别名 histone deacetylase 1; HD1; RPD3; KDAC1; GON-10; RPD3L1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Mouse
克隆类型 mouse monoclonal 抗原 HDAC1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D194908-0050 50 ul 预计5日内发货
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D194908-0100 100 ul 预计5日内发货
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产品描述

概述

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

应用

免疫印迹(WB), 免疫组织化学(IHC), 免疫荧光(IF), 流式细胞术(FCM)

属性

保存缓冲液 -20°C, PBS (PH 7.4) containing 0.05% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q13547
靶点基因 ID 3065
靶点全称 histone deacetylase 1
靶点别名 HD1; RPD3; KDAC1; GON-10; RPD3L1
靶点研究领域 Epigenetics and Nuclear Signaling, Cardiovascular, Signal Transduction
亚型 IgG1
相关文档
Sample Application

  • The image is flow cytometry analysis of Hela cells using D194908(HDAC1 antibody) at dilution 1/400 (green) and negative control (red).

  • The image is immunofluorescence of Hela cells using D194908(HDAC1 Antibody) at dilution 1/200 (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

  • The image is immunohistochemistry of paraffin-embedded Human colon tissue tissue using D194908(HDAC1 Antibody) at dilution 1/800. (Original magnification: ×200)

  • The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using D194908(HDAC1 Antibody) at dilution 1/800. (Original magnification: ×200)

  • Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane 1-4: Hela, RAW264.7, K562 and Jurkat cell lysates, Primary antibody: D194908(HDAC1 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes
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