Order NO. D194908
产品描述
概述
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
应用
免疫印迹(WB), 免疫组织化学(IHC), 免疫荧光(IF), 流式细胞术(FCM)
属性
保存缓冲液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q13547
|
靶点基因 ID |
3065
|
靶点全称 |
histone deacetylase 1
|
靶点别名 |
HD1; RPD3; KDAC1; GON-10; RPD3L1
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Cardiovascular, Signal Transduction
|
亚型 |
IgG1
|