Order NO. D194914
产品描述
概述
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
应用
免疫印迹(WB), 免疫组织化学(IHC), 免疫荧光(IF), 流式细胞术(FCM)
属性
保存缓冲液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P13647
|
靶点基因 ID |
3852
|
靶点全称 |
keratin 5
|
靶点别名 |
K5; CK5; DDD; DDD1; EBS1; EBS2; EBS2A; EBS2B; EBS2C; EBS2D; EBS2E; EBS2F; KRT5A
|
靶点研究领域 |
Signal Transduction
|
亚型 |
IgG1
|