Order NO. D194934
产品描述
概述
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.
应用
免疫印迹(WB), 免疫组织化学(IHC), 免疫荧光(IF), 流式细胞术(FCM)
属性
保存缓冲液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q93009
|
靶点基因 ID |
7874
|
靶点全称 |
ubiquitin specific peptidase 7
|
靶点别名 |
TEF1; HAUSP; HAFOUS
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Cancer, Cell Biology
|
亚型 |
IgG2b
|