Order NO. D194943
产品描述
概述
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
应用
免疫印迹(WB),流式细胞术(FCM)
属性
保存缓冲液 |
-20°C, Ascitic fluid with 0.05% sodium azide
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P07766
|
靶点基因 ID |
916
|
靶点全称 |
CD3 epsilon subunit of T-cell receptor complex
|
靶点别名 |
T3E; TCRE; IMD18; CD3epsilon
|
靶点研究领域 |
Immunology, Stem Cells
|
亚型 |
IgG1
|