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Order NO. D194973
小鼠抗CALR单克隆抗体
英文名 Anti-CALR mouse monoclonal antibody
别名 calreticulin; RO; CRT; SSA; cC1qR; HEL-S-99n
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Mouse, Rat
克隆类型 mouse monoclonal 抗原 CALR
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D194973-0050 50 ul 预计5日内发货
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D194973-0100 100 ul 预计5日内发货
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产品描述

概述

Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.

应用

免疫印迹(WB),免疫组织化学(IHC),流式细胞术(FCM)

属性

保存缓冲液 -20°C, PBS (PH 7.4) containing 0.05% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 P27797
靶点基因 ID 811
靶点全称 calreticulin
靶点别名 RO; CRT; SSA; cC1qR; HEL-S-99n
靶点研究领域 Signal Transduction
亚型 IgG2a
相关文档
Sample Application

  • The image is flow cytometry analysis of Hela cells using D194973(CALR antibody) at dilution 1/400 (green) and negative control (red).

  • The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using D194973(CALR Antibody) at dilution 1/800. (Original magnification: ×200)

  • The image is immunohistochemistry of paraffin-embedded Human bladder cancer tissue using D194973(CALR Antibody) at dilution 1/800. (Original magnification: ×200)

  • Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane 1-7: Hela, MCF-7, NIH/3T3, HepG2, Jurkat, Y-79 and C6 cell lysates, Primary antibody: D194973(CALR Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti mouse IgG at 1/10000 dilution, Exposure time: 2 minutes
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