Order NO. D195489
小鼠抗BRAF (mutated V600A)单克隆抗体
| 英文名 | Anti-BRAF (mutated V600A) mouse monoclonal antibody | ||
| 别名 | B-Raf proto-oncogene, serine/threonine kinase; NS7; B-raf; BRAF1; RAFB1; B-RAF1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Mouse | 反应种属 | Recognizes V600A mutant, but not wild-type Human BRAF |
| 标记物 | Unconjugate | 克隆类型 | mouse monoclonal |
| 抗原 | BRAF | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D195489-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. |
| Applications: | ELISA, WB, IF |
| Name of antibody: | BRAF (mutated V600A) |
| Immunogen: | A synthetic peptide from the internal region of human BRAF which includes the mutation of V600A |
| Full name: | B-Raf proto-oncogene, serine/threonine kinase |
| Synonyms: | NS7; B-raf; BRAF1; RAFB1; B-RAF1 |
| SwissProt: | P15056 |
| ELISA Recommended dilution: | 1000-5000 |
| WB Predicted band size: | 84 kDa |
| WB Positive control: | Purified His-tagged BRAF (mutated V600A) protein |
| WB Recommended dilution: | 500-1000 |
| IF Recommended dilution: | 50-100 |
相关文档
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Sample Application
