Order NO. D195523
小鼠抗EGFR (mutated G719A)单克隆抗体
| 英文名 | Anti-EGFR (mutated G719A) mouse monoclonal antibody | ||
| 别名 | epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Mouse | 反应种属 | Recognizes G719A mutant, but not wild-type Human EGFR |
| 标记物 | Unconjugate | 克隆类型 | mouse monoclonal |
| 抗原 | EGFR | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D195523-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of coronavirus disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). |
| Applications: | ELISA, WB, IF |
| Name of antibody: | EGFR (mutated G719A) |
| Immunogen: | A synthetic peptide from the internal region of human EGFR which includes the mutation of G719A |
| Full name: | epidermal growth factor receptor |
| Synonyms: | ERBB; HER1; mENA; ERBB1; PIG61; NISBD2 |
| SwissProt: | P00533 |
| ELISA Recommended dilution: | 1000-5000 |
| WB Predicted band size: | 134 kDa |
| WB Positive control: | Purified His-tagged EGFR (mutated G719A) protein |
| WB Recommended dilution: | 500-1000 |
| IF Recommended dilution: | 50-100 |
相关文档
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Sample Application
