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Order NO. D197007
小鼠抗FSCN1单克隆抗体
英文名 Anti-FSCN1 mouse monoclonal antibody
别名 fascin actin-bundling protein 1; HSN; SNL; p55; FAN1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Rat
克隆类型 mouse monoclonal 抗原 FSCN1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D197007-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

应用

免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q16658
靶点基因 ID 6624
靶点全称 fascin actin-bundling protein 1
靶点别名 HSN; SNL; p55; FAN1
靶点研究领域 Signal Transduction
亚型 IgG2a
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue, on the right is immunohistochemistry of paraffin-embedded Human thyroid cancer using D197007(FSCN1 Antibody) at dilution 1/500. (Original magnification: ×200)


  • The image is immunohistochemistry of paraffin-embedded Human pancreas tissue using D197007(FSCN1 Antibody) at dilution 1/500. (Original magnification: ×200)

  • Gel: 8%SDS-PAGE, Lysate: 35μg, Lane 1-6: 293T, MCF7, PC12, LOVO, Hela and A549 cell lysates, Primary antibody: D197007(FSCN1 Antibody) at dilution 1/500, Secondary antibody: Goat anti mouse IgG at 1/5000 dilution, Exposure time: 15 minutes
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