Order NO. D197007
产品描述
概述
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.
应用
免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q16658
|
靶点基因 ID |
6624
|
靶点全称 |
fascin actin-bundling protein 1
|
靶点别名 |
HSN; SNL; p55; FAN1
|
靶点研究领域 |
Signal Transduction
|
亚型 |
IgG2a
|