概述

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.

应用

免疫印迹（WB），免疫组织化学（IHC）

属性

保存缓冲液	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件	2-8°C
靶点 Uniprot 登记号	P08779
靶点基因 ID	3868
靶点全称	keratin 16
靶点别名	K16; PC1; CK16; K1CP; NEPPK; FNEPPK; KRT16A
靶点研究领域	Signal Transduction
亚型	IgG2a