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Order NO. D197051
小鼠抗FTO单克隆抗体
英文名 Anti-FTO mouse monoclonal antibody
别名 FTO, alpha-ketoglutarate dependent dioxygenase; GDFD; ALKBH9; BMIQ14
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human
克隆类型 mouse monoclonal 抗原 FTO
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D197051-0100 100 ul 预计5日内发货
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产品描述

概述

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

应用

免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q9C0B1
靶点基因 ID 79068
靶点全称 FTO, alpha-ketoglutarate dependent dioxygenase
靶点别名 GDFD; ALKBH9; BMIQ14
靶点研究领域 Metabolism, Neuroscience, Cardiovascular
亚型 IgG1
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human breast tissue, on the right is immunohistochemistry of paraffin-embedded Human ovarian cancer using D197051(FTO Antibody) at dilution 1/500. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human pancreas tissue, on the right is immunohistochemistry of paraffin-embedded Human endometrium tissue using D197051(FTO Antibody) at dilution 1/500. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 35μg, Lane 1-6: Jurkat, Hela, HepG2, 293T, SH-SY5Y and NCI-H460 cell lysates, Primary antibody: D197051(FTO Antibody) at dilution 1/500, Secondary antibody: Goat anti mouse IgG at 1/5000 dilution, Exposure time: 15 minutes
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