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Order NO. D197058
小鼠抗SF1单克隆抗体
英文名 Anti-SF1 mouse monoclonal antibody
别名 splicing factor 1; BBP; MBBP; ZFM1; ZNF162; D11S636; ZCCHC25
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human
克隆类型 mouse monoclonal 抗原 SF1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D197058-0100 100 ul 预计5日内发货
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产品描述

概述

This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.

应用

免疫印迹(WB)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q15637
靶点基因 ID 7536
靶点全称 splicing factor 1
靶点别名 BBP; MBBP; ZFM1; ZNF162; D11S636; ZCCHC25
靶点研究领域 Epigenetics and Nuclear Signaling
亚型 IgG1
相关文档
Sample Application

  • Gel: 8%SDS-PAGE, Lysate: 35μg, Lane 1-9: Jurkat, K562, U251, HepG2, NCI-H460, Hela, PC3, MCF7, A549 cell lysates, Primary antibody: D197058(SF1 Antibody) at dilution 1/500, Secondary antibody: Goat anti mouse IgG at 1/5000 dilution, Exposure time: 15 minutes
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