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Order NO. D197086
小鼠抗FBXO22单克隆抗体
英文名 Anti-FBXO22 mouse monoclonal antibody
别名 F-box protein 22; FBX22; FISTC1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Mouse 反应种属 Human, Mouse
克隆类型 mouse monoclonal 抗原 FBXO22
编 号 规格 库存 目录价(¥) 您的价格(¥) 数 量
D197086-0100 100 ul 预计5日内发货 待询价 待询价
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产品描述

概述

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.

应用

免疫印迹(WB)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 Q8NEZ5
靶点基因 ID 26263
靶点全称 F-box protein 22
靶点别名 FBX22; FISTC1
靶点研究领域 Cell Biology, Epigenetics and Nuclear Signaling
亚型 IgG1
相关文档
Sample Application

  • Gel: 8%SDS-PAGE, Lysate: 35μg, Lane 1-3: A549, HepG2 cell, Mouse heart tissue lysates, Primary antibody: D197086(FBXO22 Antibody) at dilution 1/500, Secondary antibody: Goat anti mouse IgG at 1/5000 dilution, Exposure time: 15 minutes