概述

This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease.

应用

免疫印迹（WB）

属性

保存缓冲液	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件	2-8°C
靶点 Uniprot 登记号	Q92673
靶点基因 ID	6653
靶点全称	sortilin related receptor 1
靶点别名	LR11; LRP9; SORLA; gp250; SorLA-1; C11orf32
靶点研究领域	Neuroscience, Signal Transduction
亚型	IgG2b