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编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D197250-0100 | 100 ul | 预计5日内发货 |
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概述
Cytochrome b-c1 complex subunit Rieske, mitochondrial: Component of the mitochondrial ubiquinol-cytochrome c reductase complex dimer (complex III dimer), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (PubMed:28673544). Incorporation of UQCRFS1 is the penultimate step in complex III assembly (By similarity). Cytochrome b-c1 complex subunit 9: Possible component of the mitochondrial ubiquinol-cytochrome c reductase complex dimer (complex III dimer), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (PubMed:28673544). UQCRFS1 undergoes proteolytic processing once it is incorporated in the complex III dimer, including this fragment, called subunit 9, which corresponds to the transit peptide (PubMed:28673544). The proteolytic processing is necessary for the correct insertion of UQCRFS1 in the complex III dimer, but the persistence of UQCRFS1-derived fragments may prevent newly imported UQCRFS1 to be processed and assembled into complex III and is detrimental for the complex III structure and function (PubMed:28673544). It is therefore unsure whether the UQCRFS1 fragments, including this fragment, are structural subunits (PubMed:28673544).
应用
免疫印迹(WB),免疫组织化学(IHC),免疫荧光(IF)
属性
保存缓冲液 | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | P47985 |
靶点基因 ID | 7386 |
靶点全称 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 |
靶点别名 | RIP1; RIS1; RISP; UQCR5 |
靶点研究领域 | Metabolism, Cell Biology, Cancer |
亚型 | IgG2a |