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Order NO. D198208
小鼠抗SDHB单克隆抗体
英文名 Anti-SDHB mouse monoclonal antibody
别名 CWS2; IP; PGL4; SDH; SDH1; SDH2; SDHIP
相关类别 一抗 储存 冷冻(-20℃) 避光
宿主 Mouse 反应种属 Human
克隆类型 mouse monoclonal 抗原 SDHB
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D198208-0100 100 ul 预计5日内发货
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产品描述

概述

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

应用

免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件 2-8°C
靶点 Uniprot 登记号 P21912
靶点基因 ID 6390
靶点全称 succinate dehydrogenase complex iron sulfur subunit B
靶点别名 IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP
靶点研究领域 Metabolism, Cancer, Cell Biology
亚型 IgG1
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded adenocarcinoma of human endometrium tissue, on the right is immunohistochemistry of paraffin-embedded human Kidney tissue using D198208(SDHB Antibody) at dilution 1/40. (Original magnification: ×200)


  • Gel: 10%SDS-PAGE, Lysate: 10μg, Lane 1-8: HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, MCF-7 cell lysates, Primary antibody: D198208(SDHB Antibody) at dilution 1/200, Secondary antibody: Goat anti mouse IgG at 1/8000 dilution, Exposure time: 15 minutes
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