Order NO. D198261
产品描述
概述
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
应用
免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P16234
|
靶点基因 ID |
5156
|
靶点全称 |
platelet derived growth factor receptor alpha
|
靶点别名 |
CD140A; PDGFR2; PDGFR-2
|
靶点研究领域 |
Cardiovascular, Signal Transduction, Cancer
|
亚型 |
IgG1
|