概述

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants.

应用

免疫组织化学（IHC）

属性

保存缓冲液	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
运输条件	2-8°C
靶点 Uniprot 登记号	Q96IY4
靶点基因 ID	1361
靶点全称	carboxypeptidase B2
靶点别名	CPU; PCPB; TAFI
靶点研究领域	Cardiovascular, Metabolism
亚型	IgG1