Order NO. D198624
产品描述
概述
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
应用
免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q9Y572
|
靶点基因 ID |
11035
|
靶点全称 |
receptor interacting serine/threonine kinase 3
|
靶点别名 |
RIP3
|
靶点研究领域 |
Cancer, Signal Transduction, Immunology
|
亚型 |
IgG1
|