Order NO. D198788
小鼠抗APEX1单克隆抗体
| 英文名 | Anti-APEX1 mouse monoclonal antibody | ||
| 别名 | APE; APE1; APEN; APEX; APX; HAP1; REF1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） 避光 |
| 宿主 | Mouse | 反应种属 | Human , Dog , Rat , Monkey , Mouse |
| 克隆类型 | mouse monoclonal | 抗原 | APEX1 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D198788-0100 | 100 ul | 预计5日内发货 |
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产品描述
概述
The APEX gene encodes the major AP endonuclease in human cells. It encodes the APEX endonuclease, a DNA repair enzyme with apurinic/apyrimidinic (AP) activity. Such AP activity sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. The AP sites are the most frequent pre-mutagenic lesions that can prevent normal DNA replication. Splice variants have been found for this gene; all encode the same protein. Disruptions in the biological functions related to APEX are associated with many various malignancies and neurodegenerative diseases.
应用
免疫印迹（WB），免疫组织化学（IHC）
属性
| 保存缓冲液 | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | P27695 |
| 靶点基因 ID | 328 |
| 靶点全称 | apurinic/apyrimidinic endodeoxyribonuclease 1 |
| 靶点别名 | APE; APX; APE1; APEN; APEX; HAP1; REF1 |
| 靶点研究领域 | Epigenetics and Nuclear Signaling, Cardiovascular |
| 亚型 | IgG2b |
相关文档
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